A curated repository of information on active pharmaceutical ingredients (APIs) used in contraceptives
Estradiol (E2) is a natural estrogen and the primary female sex hormone. E2 and its esters, including estradiol cypionate and estradiol valerate, are used in…
Estradiol Cypionate (EV or E2V) is an ester prodrug of estradiol and is used in place of estradiol in some medications.
Estradiol Valerate (EV, E2V) is an ester prodrug of estradiol and is used in place of estradiol in some medications.
Ethinyl estradiol (EE) is a synthetic estrogen derivative used alongside progestins in a large majority of combined oral contraceptives for better cycle control and to…
Mestranol (EEME) is a synthetic steroidal estrogen and a biologically inactive prodrug of ethinyl estradiol. It is used alongside progestins in combined oral contraceptives and…
Quinestrol is a synthetic estrogen and prodrug of ethinyl estradiol. It is used in hormone replacement therapy and in the treatment of some cancers, as…
Chlormadinone acetate (CMA) is a progestin and antiandrogen. It is used in combined oral contraceptives and in treating gynecological disorders.
Cyproterone Acetate (CPA) is a steroidal progestogen and potent antiandrogen. It is used in oral contraceptives, as a component of hormone therapy, and in the…
Desogestrel (DSG) is a synthetic progestin and prodrug of etonogestrel (ENG), derived from testosterone and used in hormonal contraceptives. DSG is primarily used in oral…
Dienogest (DNG) is a progestogen used in hormonal contraceptives and for the treatment of endometriosis.
Drospirenone (DRSP) is a synthetic progestogen used in combined oral contraceptives and hormone replacement therapy. Unlike other progestins, DRSP is a spirolactone, instead of a…
Ethynodiol diacetate is a synthetic progestogen used in hormonal contraceptives. It is a prodrug of ethynodiol, which is a prodrug of norethindrone.
Etonogestrel (ENG) is a synthetic progestin derived from testosterone and used in hormonal contraceptives. Etonogestrel is primarily used in implants and vaginal rings, while its…
Gestodene (GSD) is a synthetic progestogen used in combined oral contraceptives. It is available in Europe but not the US.
Levonorgestrel (LNG) is a synthetic progestational hormone used in hormonal contraceptives and as a component in hormone replacement therapy. It is the biologically active form…
Lynestrenol is a synthetic progestogen used in oral contraceptives and treatments of other disorders. It is a prodrug of norethindrone, therefore its pharmacology is almost…
Medroxyprogesterone acetate (MPA) is a synthetic progestogen used in hormonal contraceptives, as a component in hormone replacement therapy, and in treatment for various other medical…
Megestrol Acetate (MGA) is a synthetic progestogen that was formerly used in combined oral contraceptives. It is currently used as an appetite stimulant and in…
Nestorone (NES) is a synthetic progestogen designed with high specificity for the progesterone receptor. It is being investigated for use in hormonal contraceptives but is…
Nomegestrol acetate (NOMAC) is a synthetic progestogen used in hormonal contraceptives, hormone replacement therapy, and for the treatment of gynecological disorders. It is available internationally,…
Norelgestromin (NGMN) is a synthetic progestogen used in combined oral contraceptives and in menopausal hormonal therapy. It is the primary metabolite of norgestimate.
Norethindrone (NET), or norethisterone, is a synthetic progestogen derived from testosterone and used in hormonal contraceptives, hormone replacement therapy, and treatment of gynecological disorders. Prodrugs…
Norethindrone acetate (NETA), or norethisterone acetate, is an ester prodrug of norethindrone. It is a synthetic progestogen used in place of norethindrone in some hormonal…
Norethindrone enanthate (NETE), or norethisterone enanthate, is an ester prodrug of norethindrone. It is a synthetic progestogen used in place of norethindrone in some hormonal…
Norethynodrel (NOR) is a synthetic progestogen used in hormonal contraceptives and for the treatment of gynecological disorders. It is generally no longer used. It is…
Norgestimate is a synthetic progestogen used in combined oral contraceptives and hormone replacement therapy. It is a prodrug of norelgestromin, and, to a much lesser…
Norgestrel is a synthetic progestogen used in combined oral contraceptives. It is a racemic mix of the stereoisomers dextronorgestrel and levonorgestrel. As dextronorgestrel is biologically…