Estradiol Cypionate (EV or E2V) is an ester prodrug of estradiol and is used in place of estradiol in some medications.
Abbreviation
EC, E2C
References
Names
References
CASRN
313-06-4
References
PubChem CID
9403
ECHA InfoCard
DrugBank Accession Number
DBSALT000067
References
UNII
7E1DV054LO
KEGG Entry Number
D04063
Wikipedia Entry Name
Estradiol Cypionate
ChEBI ID
CHEBI:34745
ChEMBL ID
CHEMBL1200973
ChemSpider ID
9033
NIST
Estradiol Cypionate
Molecular Formula
C26H36O3
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Molecular Weight
369.56 g/mol
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Specific Optical Rotation
+39° to +44°, 20 mg/mL in dioxane
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GHS Hazard Code(s)
Class | Category | Code | Description |
---|---|---|---|
Acute Oral Toxicity | 4 | H302 | Harmful if swallowed |
Acute Dermal Toxicity | 4 | H312 | Harmful in contact with skin |
Acute Inhalation Toxicity | 4 | H332 | Harmful if inhaled |
Carcinogenicity | 1B | H350 | May cause cancer |
Reproductive Toxicity | 1B | H360 | May damage fertility or the unborn child |
MRTD
0.5 mg/kg/day
Pharmacology
See estradiol
References
Estrogen Receptor Activity
Agonist
Metabolism
Metabolized by CYP3A4, CYP2C9, UGT
Enzyme Interactions
Inhibits CYP3A4, CYP2C9, CYP2B6 Induces UGTs
50-28-2
Discontinued
085603
Discontinued
017968
Discontinued; Prescription
085470