1. APIs
  2. Mestranol
  3. Impurities
  4. 17α-Ethinyl-17-hydroxy-3-methoxyestra-1,3,5(10)-triene-6-one

17α-Ethinyl-17-hydroxy-3-methoxyestra-1,3,5(10)-triene-6-one

Structure

Notes

Thermal (147 or 178 °C) degradation product.

Appearance

Pale yellow needles

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References

  1. Li, H.; Song, Y.; Peng, X. Improved Synthesis of Mestranol and Ethinyl Estradiol (EE) Related Degradation Products as Authentic References. Steroids 2008, 73 (5), 488–494.
    2. (View all citations for this reference)

Melting Point

161.8-162.5 °C

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References

  1. Li, H.; Song, Y.; Peng, X. Improved Synthesis of Mestranol and Ethinyl Estradiol (EE) Related Degradation Products as Authentic References. Steroids 2008, 73 (5), 488–494.
    2. (View all citations for this reference)

Spectra

1H NMR, IR, and EI MS peaks available.

library_books

References

  1. Li, H.; Song, Y.; Peng, X. Improved Synthesis of Mestranol and Ethinyl Estradiol (EE) Related Degradation Products as Authentic References. Steroids 2008, 73 (5), 488–494.
    2. (View all citations for this reference)

References

  1. Li, H.; Song, Y.; Peng, X. Improved Synthesis of Mestranol and Ethinyl Estradiol (EE) Related Degradation Products as Authentic References. Steroids 2008, 73 (5), 488–494.
    2. (View all citations for this reference)
  2. Cotter, M. L.; Levine, S. D.; Mallory, R.; Shaw, C. Thermal Degradation of Mestranol and Ethinyl Estradiol. Tetrahedron Lett. 1978, 19 (22), 1939–1942. (View all citations for this reference)