1. APIs
  2. Ethynodiol Diacetate
  3. Impurities
  4. 3α-Ethynodiol Diacetate

3α-Ethynodiol Diacetate

Structure

Other Names & Identifiers

  • α-Ethynodiol Diacetate

Notes

Reduction of 3-keto group of norethindrone is not entirely stereoselective, resulting in this impurity in the synthesis of ethynodiol diacetate.

Limits

1.5%

References

  1. Babják, M.; Balogh, G.; Gazdag, M.; Görög, S. Estimation of Impurity Profiles of Drugs and Related Materials: Part XXI. HPLC/UV/MS Study of the Impurity Profile of Ethynodiol Diacetate. J. Pharm. Biomed. Anal. 2002, 29 (6), 1153–1157. (View all citations for this reference)
  2. USP 40: Ethynodiol Diacetate monograph.
    3. (View all citations for this reference)