1. APIs
  2. Ethinyl Estradiol
  3. Impurities
  4. 1-Methyl-ethinylestradiol

1-Methyl-ethinylestradiol

Structure

MOL SDF CML

Other Names & Identifiers

  • BP Ethinylestradiol Impurity J
  • 1-methyl-19-nor-17α-pregna-1,3,5(10)-trien-20-yne-3,17-diol

CASRN

15071-66-6

Molecular Formula

C21H26O2

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Molecular Weight

310.436 g/mol

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Structural Difference from API

The H EE's C1 is replaced with a methyl group

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References

  1. British Pharmacopoeia 2017: Ethinylestradiol monograph
    2. (View all citations for this reference)

Source from API

Methylation or side product

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Melting Point

135 - 137° C

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Reaxys ID #

3156862

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

PubChem CID

232402

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)
  2. National Center for Biotechnology Information. PubChem Compound Database; CID=11150565. (View all citations for this reference)

Limits

0.1%

References

  1. European Pharmacopoeia 8.2 Ethinyl Estradiol
    2. (View all citations for this reference)
  2. British Pharmacopoeia 2017: Ethinylestradiol monograph
    3. (View all citations for this reference)