1. APIs
  2. Estradiol
  3. Impurities
  4. Estra-1,3,5(10),9(11)-tetraene-3,17β-diol

Estra-1,3,5(10),9(11)-tetraene-3,17β-diol

Structure

MOL SDF CML

Other Names & Identifiers

  • BP Estradiol Hemihydrate Impurity D

CASRN

791-69-5

Notes

ID in reference: 10. Formed from oxidative degradation of estradiol. (mechanism: E2 -> Impurity 1 + 2 + 3).

Molecular Formula

C18H22O2

References

Molecular Weight

270.37 g/mol

References

References

  1. BP 2017 Estradiol Hemihydrate monograph.
    2. (View all citations for this reference)
  2. Beni, Z.; Hada, V.; Varga, E.; Maho, S.; Aranyi, A.; Szantay, C., New oxidative decomposition mechanism of estradiol through the structural characterization of a minute impurity and its degradants. J. Pharm. Biomed. Anal. 2013, 78-79, 183-189.
    3. (View all citations for this reference)