1. APIs
  2. Ethynodiol Diacetate
  3. Impurities
  4. Ethynodiol 17-Monoacetate

Ethynodiol 17-Monoacetate

Structure

Notes

Less likely to be present than the 3-monoacetyl derivative, as the 3β-hydroxyl group is much more reactive than the 17β-hydroxyl.

References

  1. Babják, M.; Balogh, G.; Gazdag, M.; Görög, S. Estimation of Impurity Profiles of Drugs and Related Materials: Part XXI. HPLC/UV/MS Study of the Impurity Profile of Ethynodiol Diacetate. J. Pharm. Biomed. Anal. 2002, 29 (6), 1153–1157. (View all citations for this reference)
  2. Gorog, S., Chemical and analytical characterization of related organic impurities in drugs. Anal. Bioanal. Chem. 2003, 377 (5), 852-862.
    3. (View all citations for this reference)