1. APIs
  2. Megestrol Acetate
  3. Metabolites

Megestrol Acetate Metabolites

Name Structure Notes
17α-Acetoxy-2α-hydroxy-6-hydroxymethylpregna-4,6-diene-3,20-dione structure Metabolized in liver. Also found as glucuronide conjugate.
17α-Acetoxy-6-hydroxymethylpregna-4,6-diene-3,20-dione structure Metabolized in liver. Also found as glucuronide conjugate.
17α-Acetoxy-2α-hydroxy-6-methylpregna-4,6-diene-3,20-dione structure Metabolized in liver. Also found as glucuronide conjugate.
Megestrol Acetate Metabolites Two oxidative metabolites observed: MS-1 and MS-2. MS-1 identified as an alcohol, MS-2 is unknown. Their chemical structures were not specified.