1. APIs
  2. Gestodene
  3. Gestodene Metabolites
  4. 3β,5α-tetrahydrogestodene

3β,5α-tetrahydrogestodene

Structure

Notes

Significantly reduced progestational activity compared to gestodene. Selectively activates ERα.

References

  1. Larrea, F.; Garcia-Becerra, R.; Lemus, A. E.; Garcia, G. A.; Perez-Palacios, G.; Jackson, K. J.; Coleman, K. M.; Dace, R.; Smith, C. L.; Cooney, A. J., A-ring reduced metabolites of 19-nor synthetic progestins as subtype selective agonists for ER alpha. Endocrinology 2001, 142 (9), 3791-3799.
    2. (View all citations for this reference)