1. APIs
  2. Norethindrone
  3. Metabolites

Norethindrone Metabolites

Name Structure Notes
Other Norethindrone Metabolites Sulfate and glucuronide conjugates of norethindrone and its metabolites are also present.
19-Norandrosterone structure The epimer 19-noretiocholanolone may also be formed by metabolism of NET. Detection of 19-norandrosterone in an athlete's urine is taken as evidence of doping by nandrolone or another 19-steroid. However, this compound is a metabolite of norethindrone, and as a metabolite, it can be detected in quantities above the reporting threshold of 2 ng/mL.
5α-Dihydronorethindrone structure Major metabolite.
5β-Dihydronorethindrone structure
3β,5β-Tetrahydronorethindrone structure
3β,5α-Tetrahydronorethindrone structure
3α,5β-Tetrahydronorethindrone structure
3α,5α-Tetrahydronorethindrone structure
Norethynodrel structure
Ethinyl Estradiol structure Primary metabolite of mestranol and quinestrol. Also a minor metabolite of norethindrone (0.7 and 1.0% of norethindrone converted to ethinyl estradiol at doses of 5 and 10 mg, respectively).