APIs
(current)
Estrogens
Estradiol
Estradiol Cypionate
Estradiol Valerate
Ethinyl Estradiol
Mestranol
Quinestrol
Progestins
Chlormadinone Acetate
Cyproterone Acetate
Desogestrel
Dienogest
Drospirenone
Ethynodiol Diacetate
Etonogestrel
Gestodene
Levonorgestrel
Lynestrenol
Medroxyprogesterone Acetate
Megestrol Acetate
Nestorone
Nomegestrol Acetate
Norelgestromin
Norethindrone
Norethindrone Acetate
Norethindrone Enanthate
Norethynodrel
Norgestimate
Norgestrel
SPRMs
Ulipristal Acetate
SERMs
Ormeloxifene
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Citations for: Abrams, L. S.; Skee, D.; Natarajan, J.; Wong, F. A. Pharmacokinetic Overview of Ortho Evra (TM)/Evra (TM). Fertil. Steril. 2002, 77 (2, 2), S3–S12.
Entry Type
Name
Value
Parent Entry
Pharmacology Data Field
Serum Protein Binding
Binds to SHBG
Norgestrel (API)
Pharmacology Data Field
Elimination Half-Life (t
1/2
)
29.2 +/- 14.5 h from IV injection of 252 μg norelgestromin and 25 μg ethinyl estradiol.
28.4 +/- 12.8 h from transdermal patch of 150 μg/day norelgestromin and 20 μg/day ethinyl estradiol.
Norelgestromin (API)
Pharmacology Data Field
Serum Protein Binding
>97% bound, primarily to albumin. No binding to SHBG, except as metabolite norgestrel.
Norelgestromin (API)
Pharmacology Data Field
Clearance
7.89 +/- 1.63 L/h from IV injection of 252 μg norelgestromin and 25 μg ethinyl estradiol.
Norelgestromin (API)