Citations for: Abrams, L. S.; Skee, D.; Natarajan, J.; Wong, F. A. Pharmacokinetic Overview of Ortho Evra (TM)/Evra (TM). Fertil. Steril. 2002, 77 (2, 2), S3–S12.

Entry Type
Name
Value
Parent Entry
Pharmacology Data Field
Binds to SHBG
Norgestrel (API)
Pharmacology Data Field
  • 29.2 +/- 14.5 h from IV injection of 252 μg norelgestromin and 25 μg ethinyl estradiol.
  • 28.4 +/- 12.8 h from transdermal patch of 150 μg/day norelgestromin and 20 μg/day ethinyl estradiol.
Norelgestromin (API)
Pharmacology Data Field
>97% bound, primarily to albumin. No binding to SHBG, except as metabolite norgestrel.
Norelgestromin (API)
Pharmacology Data Field
7.89 +/- 1.63 L/h from IV injection of 252 μg norelgestromin and 25 μg ethinyl estradiol.
Norelgestromin (API)