Citations for: BP 2017: Cyproterone Acetate monograph.

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
Appearance
White or almost white crystalline powder
Cyproterone Acetate (API)
Physical & Chemical Properties Data Field
Melting Point
BP: About 210 °C
DrugBank, IARC, Toxnet: 200-201 °C
Cyproterone Acetate (API)
Physical & Chemical Properties Data Field
Solubility
Practically insoluble in water, very soluble in methylene chloride, freely soluble in acetone, soluble in methanol, sparingly soluble in anhydrous ethanol
Cyproterone Acetate (API)
Physical & Chemical Properties Data Field
Specific Optical Rotation
+152 to +157, 0.25 g dried substance in acetone, dilute to 25.0 mL
Cyproterone Acetate (API)
Impurity
3,20-Dioxo-1β,2β-dihydro-3′H-cyclopropa[1,2]pregna-1,4,6-trien-17-yl Acetate
N/A
Impurity
6-Methoxy-3,20-dioxo-1β,2β-dihydro-3′H-cyclopropa[1,2]pregna-1,4,6-trien-17-yl Acetate
N/A
Impurity
6-Chloro-1α-(chloromethyl)-3,20-dioxopregna-4,6-dien-17-yl Acetate
N/A
Impurity
1α-(Chloromethyl)-3,6,20-trioxopregn-4-en-17-yl Acetate
N/A
Impurity
3,6,20-Trioxo-1β,2β-dihydro-3′H-cyclopropa[1,2]pregna-1,4-dien-17-yl Acetate
N/A
Impurity
Cyproterone
N/A
Impurity
3,20-Dioxopregna-1,4-diene-17-yl Acetate
N/A
Impurity
6-Chloro-3,20-dioxopregna-1,4,6-trien-17-yl Acetate
N/A
Impurity
6α,7α-Epoxy-3,20-dioxo-1β,2β-dihydro-3′H-cyclopropa[1,2]pregna-1,4-dien-17-yl Acetate
N/A
Impurity
Cyproterone Acetate Chlorohydrin Derivative
N/A
Identifiers Data Field
Names
6-chloro-3,20-dioxo-1β,2β-dihydro-3'H-cyclopropa[1,2]pregna-1,4,6-trien-17-yl acetate
Cyproterone Acetate (API)