Citations for: BP 2017: Dienogest monograph.

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
Appearance
White, almost white, or slightly yellow crystalline powder
Dienogest (API)
Physical & Chemical Properties Data Field
Solubility
Practically insoluble in water, sparingly soluble in methylene chloride, slightly soluble in methanol
Dienogest (API)
Impurity
(11,17-Dihydroxy-3-oxoestra-4,9-dien-17α-yl)acetonitrile
N/A
Impurity
Estra-4,9-diene-3,17-dione
N/A
Impurity
[17-Hydroxy-3-oxoestra-5(10),9(11)-dien-17α-yl]acetonitrile
N/A
Impurity
[17′-Hydroxyspiro[1,3-dioxolan-2,3′-estra-5′(10′),9′(11′)-dien]-17’α-yl]acetonitrile
N/A
Impurity
[17-Hydroxy-3,3-dimethoxyestra-5(10),9(11)-dien-17α-yl]acetonitrile
N/A
Impurity
(17-Hydroxy-3-oxoestr-4-en-17α-yl)acetonitrile
N/A
Impurity
[3,17-Dihydroxyestra-1,3,5(10),9(11)-tetraen-17α-yl]acetonitrile
N/A
Impurity
[3,17-Dihydroxyestra-1,3,5(10)-trien-17α-yl]acetonitrile
N/A
Impurity
[17-Hydroxy-3-oxoestra-5(10)-en-17α-yl]acetonitrile
N/A
Impurity
[17-Hydroxy-3-methoxyestra-1,3,5(10)-trien-17α-yl]acetonitrile
N/A
Impurity
(11-Hydroperoxy-17-hydroxy-3-oxoestra-4,9-dien-17α-yl)acetonitrile
N/A
Impurity
Spiro[1,3-dioxolan-2,3′-estra-5′(10′),9′(11′)-dien]-17′-one
N/A
Impurity
(4-Bromo-17-hydroxy-3-oxoestra-4,9-dien-17α-yl)acetonitrile
N/A
Physical & Chemical Properties Data Field
Specific Optical Rotation
-352 to -344, 0.125 g dried substance in methanol, diluted to 25.0 mL
Dienogest (API)