Citations for: ChemIDPlus: A Toxnet Database. Ethinylestradiol.

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
Solubility
BP: practically insoluble in water.
PubChem: 11.3 mg/L water at 27 °C.
PubChem, BP: 1 part in 6 of ethanol, 1 in 4 of ether, 1 in 5 of acetone, 1 in 4 of dioxane, and 1 in 20 of chloroform. Soluble in vegetable oils, and in solutions of fixed alkali hydroxides (e.g. NaOH, KOH)
Ethinyl Estradiol (API)
Physical & Chemical Properties Data Field
logP
3.67
Ethinyl Estradiol (API)
Toxicology Data Field
LD50
  • mouse intraperitoneal: 0.250 g/kg
  • mouse oral: 0.950 g/kg (ChemIDPlus), 1737 mg/kg (PubChem)
  • mouse subcutaneous: > 3 g/kg
  • rat intraperitoneal: 0.471 g/kg
  • rat oral: 0.960 g/kg (PubChem: 1200 mg/kg and > 5000 mg/kg)
  • rat subcutaneous: > 2 g/kg
Ethinyl Estradiol (API)