Citations for: European Medicines Agency Evaluation of Medicines for Human Use. CHMP Assessment Report for Esmya (Ulipristal Acetate). 15 December 2011.

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
Appearance
White to yellow crystalline powder
Ulipristal Acetate (API)
Physical & Chemical Properties Data Field
Solubility
Freely soluble in CHCl3, soluble in methanol, acetone, ethanol, and insoluble in water.
Ulipristal Acetate (API)
Toxicology Data Field
Genotoxicity
"No genotoxic potential was evident in any of the test systems when tested up to appropriate concentrations and dose levels according to guidelines."
Ulipristal Acetate (API)
Physical & Chemical Properties Data Field
Polymorphism
Two found
Ulipristal Acetate (API)
Toxicology Data Field
LD50
< 1250 mg/kg (rat), >1250 mg/kg (rabbit)
Ulipristal Acetate (API)
Pharmacology Data Field
Other
Does not appear to be a P-gp substrate
Ulipristal Acetate (API)