Citations for: Lemus, A. E.; Zaga, V.; Santillan, R.; Garcia, G. A.; Grillasca, I.; Damian-Matsumura, P.; Jackson, K. J.; Cooney, A. J.; Larrea, F.; Perez-Palacios, G., The oestrogenic effects of gestodene, a potent contraceptive progestin, are mediated by its A-ring reduced metabolites. Journal of Endocrinology 2000, 165 (3), 693-702.

Entry Type
Name
Value
Parent Entry
Metabolites Data Field
Estrogen Receptor Activity
Binds to ER.
3α,5α-Tetrahydronorethindrone (Metabolite)
Metabolites Data Field
Progestogen Receptor Activity
Significantly reduced progestational activity
3β,5α-Tetrahydronorethindrone (Metabolite)
Metabolites Data Field
Estrogen Receptor Activity
selectively activates ERα. "Able to activate gene transcription via ER, although its binding affinity is lower than estradiol."
3β,5α-Tetrahydronorethindrone (Metabolite)
Metabolites Data Field
Analytical Properties & Spectra
Melting point, IR bands, 1H NMR, 13C NMR, FAB MS.
5α-Dihydronorethindrone (Metabolite)