Citations for: PubChem: Medroxyprogesterone Acetate.

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
PubChem: 214.5° C
IARC: 207-209 °C
Medroxy­progesterone Acetate (API)
Physical & Chemical Properties Data Field
3.5
Medroxy­progesterone Acetate (API)
Pharmacology Data Field
  • Competitive inhibitor of 3β-hydroxysteroid dehydrogenase/Δ5-4 isomerase II (3β-HSDII), which is essential for the biosynthesis of sex steroids and corticosteroids.
  • CYP3A4: substrate, inducer
  • CYP2C8, CYP2C9: inhibitor
Medroxy­progesterone Acetate (API)
Identifiers Data Field
6279
Medroxy­progesterone Acetate (API)
Pharmacology Data Field
Used as a contraceptive and to treat secondary amenorrhea, abnormal uterine bleeding, pain associated with endometriosis, endometrial and renal cell carcinomas, paraphilia in males, GnRH-dependent forms of precocious puberty, as well as to prevent endometrial changes associated with estrogens.
Medroxy­progesterone Acetate (API)