Citations for: Rebar, R. W.; Zeserson, K., CHARACTERISTICS OF THE NEW PROGESTOGENS IN COMBINATION ORAL-CONTRACEPTIVES. Contraception 1991, 44 (1), 1-10.

Entry Type
Name
Value
Parent Entry
Pharmacology Data Field
Serum Protein Binding
95.5-99% bound. 66% to albumin, 32% to SHBG.
Etonogestrel (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
Binds. Activity reports vary slightly: reported as an antagonist (Ruan, Lello, Kuhl), while Africander reports that some antagonist activity is seen in rat models and Stanczyk claims it to be relatively weak compared to progesterone.
Gestodene (API)
Pharmacology Data Field
Serum Protein Binding
75% to SHBG, 24% to albumin, 0.6% free (exact percentages vary depending on treatment)
Gestodene (API)
Pharmacology Data Field
Inhibition of Ovulation
0.25 mg/day
Norgestimate (API)
Pharmacology Data Field
Inhibition of Ovulation
0.04 mg/day
Gestodene (API)
Pharmacology Data Field
Inhibition of Ovulation
0.06 mg/day
Desogestrel (API)
Pharmacology Data Field
Transformation of Endometrium
2.5 mg/cycle
Desogestrel (API)
Pharmacology Data Field
Inhibition of Ovulation
0.5 mg/day
Norethindrone (API)
Pharmacology Data Field
Transformation of Endometrium
5-10 mg/cycle
Norgestimate (API)
Pharmacology Data Field
Transformation of Endometrium
100-150 mg/cycle
Norethindrone (API)
Pharmacology Data Field
Menstrual Delay
10-15 mg/day
Norethindrone (API)
Pharmacology Data Field
Menstrual Delay
5 mg/day
Norgestimate (API)
Pharmacology Data Field
Transformation of Endometrium
2-3 mg/cycle
Gestodene (API)
Pharmacology Data Field
Menstrual Delay
~0.2 mg/day
Gestodene (API)
Pharmacology Data Field
Inhibition of Ovulation
0.05-0.1 mg/day
Levonorgestrel (API)
Pharmacology Data Field
Transformation of Endometrium
5-6 mg/cycle
Levonorgestrel (API)
Pharmacology Data Field
Menstrual Delay
0.25-1.0 mg/day
Levonorgestrel (API)
Pharmacology Data Field
Menstrual Delay
~0.25 (mg/day
Desogestrel (API)