Citations for: (1) Reimann, R.; Kalweit, S.; Lang, R. Studies for a Genotoxic Potential of Some Endogenous and Exogenous Sex Steroids. II. Communication: Examination for the Induction of Cytogenetic Damage Using the Chromosomal Aberration Assay on Human Lymphocytes in Vitro and the Mouse Bone Marrow Micronucleus Test in vivo. Environ. Mol. Mutagen. 1996, 28 (2), 133–144.

Entry Type
Name
Value
Parent Entry
Toxicology Data Field
Genotoxicity
Not found to be genotoxic in human lymphocyte assay in vitro and mouse bone marrow micronucleus test in vivo.
Ethinyl Estradiol (API)
Toxicology Data Field
Genotoxicity
Reports vary. Siddique et al. found CPA to be genotoxic to human lymphocytes at 20 and 30 μm using chromosomal aberrations, mitotic index, and sister chromatid exchanges. Reimann et al. did not find CPA to be genotoxic in human lymphocyte assay in vitro and mouse bone marrow micronucleus test in vivo.
Cyproterone Acetate (API)
Toxicology Data Field
Genotoxicity
Not found to be genotoxic in human lymphocyte assay in vitro and mouse bone marrow micronucleus test in vivo.
Drospirenone (API)