Citations for: Ruan, X.; Seeger, H.; Mueck, A. O., The pharmacology of dienogest. Maturitas 2012, 71 (4), 337-44.

Entry Type
Name
Value
Parent Entry
Pharmacology Data Field
Androgen Receptor Activity
Antagonist (40% of CPA, the most potent anti-androgenic progestin)
Dienogest (API)
Pharmacology Data Field
Estrogen Receptor Activity
Weak or no agonist and antagonist activity
Dienogest (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
Low to no activity
Dienogest (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Dienogest (API)
Pharmacology Data Field
Bioavailability
90-96.2%
Dienogest (API)
Pharmacology Data Field
Elimination Half-Life (t1/2)
8-10 h
Dienogest (API)
Pharmacology Data Field
Serum Protein Binding
90% bound to serum albumin, 10% free. No binding to SHBG or CBG.
Dienogest (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
Reported as "weak" (Africander, Kuhl) and "active" (Ruan, Lello) agonist
Gestodene (API)