Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
BP: About 210 °C
DrugBank, IARC, Toxnet: 200-201 °C
Cyproterone Acetate (API)
Pharmacology Data Field
88%
Cyproterone Acetate (API)
Pharmacology Data Field
Drugbank: 38 h (oral), 96 h (intramuscular)
Toxnet: 43.9 +/- 12.8 h from two 50 mg CPA tablets
Cyproterone Acetate (API)
Pharmacology Data Field
Almost exclusively bound to albumin. 3.5-4% unbound.
Cyproterone Acetate (API)
Toxicology Data Field
Reports vary. Siddique et al. found CPA to be genotoxic to human lymphocytes at 20 and 30 μm using chromosomal aberrations, mitotic index, and sister chromatid exchanges. Reimann et al. did not find CPA to be genotoxic in human lymphocyte assay in vitro and mouse bone marrow micronucleus test in vivo.
Cyproterone Acetate (API)
Physical & Chemical Properties Data Field
Store in a tightly closed container in a dry, ventilated location, recommended at 2-8 °C. Do not store above 25 °C.
Cyproterone Acetate (API)
Pharmacology Data Field
285 ng/mL from two 50 mg CPA tablets
Cyproterone Acetate (API)
Toxicology Data Field
rat intraperitoneal: 565 mg/kg
mouse intraperitoneal: 3300 mg/kg
Cyproterone Acetate (API)