Citations for: Toxnet: Norethindrone.

Entry Type

Name

Value

Parent Entry

Physical & Chemical Properties Data Field

Melting Point

Zafar: 201-203 °C
IARC, Toxnet: 203-204 °C

Norethindrone (API)

Physical & Chemical Properties Data Field

logP

2.97

Norethindrone (API)

Pharmacology Data Field

Elimination Half-Life (t_1/2)

7-8 h (Stanczyk, Goodman & Gilman)
4.8 - 12.8 h (Toxnet)

Norethindrone (API)

Pharmacology Data Field

Serum Protein Binding

> 95%, 61% to albumin, 36% to SHBG

Norethindrone (API)

Pharmacology Data Field

Apparent Volume of Distribution

4 L/kg

Norethindrone (API)

Pharmacology Data Field

Clearance

0.4 L/h/kg

Norethindrone (API)

Physical & Chemical Properties Data Field

Storage Conditions

Stable in air, unstable when exposed to both air and light.

Norethindrone (API)

Toxicology Data Field

LD₅₀

LD₅₀, mouse oral: 6 g/kg
TD_Lo, human women oral: 42 mg/kg

Norethindrone (API)