1. APIs
  2. Ethinyl Estradiol
  3. Impurities
  4. 17α-Estradiol
  1. APIs
  2. Estradiol
  3. Impurities
  4. 17α-Estradiol

17α-Estradiol

Structure

MOL SDF CML

Other Names & Identifiers

  • BP Estradiol Hemihydrate Impurity B
  • BP Ethinylestradiol Impurity L

CASRN

57-91-0

Molecular Formula

C18H24O2

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Molecular Weight

272.39 g/mol

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Melting Point

222 - 226° C

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Structural Differences from API

The OH and ethyne groups at C17 in Ethinyl Estradiol are replaced respectively with an H group and an OH group.

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References

  1. BP 2015; vol. I, pages 903 - 905
    2. (View all citations for this reference)

Source from API

Ethinyl estradiol: Possible synthetic side product; oxidation; functional group substitution.

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

Reaxys ID

2698044

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References

  1. Online Subscription Database. Reed Elsevier Properties SA. (View all citations for this reference)

PubChem ID

68570

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References

  1. National Center for Biotechnology Information. PubChem Compound Database; CID=11150565. (View all citations for this reference)

Limits

0.10%

References

  1. European Pharmacopoeia 8.2 Ethinyl Estradiol
    2. (View all citations for this reference)
  2. BP 2017 Estradiol Hemihydrate monograph.
    3. (View all citations for this reference)