Entry Type
Name
Value
Parent Entry
Impurities Data Field
The H group on EE's C2 is replaced with a methyl group
2-Methyl-ethinylestradiol (Impurity)
Impurities Data Field
Possible ortho methylation
2-Methyl-ethinylestradiol (Impurity)
Impurities Data Field
The OH and ethyne groups at C17 in Ethinyl Estradiol are replaced respectively with an H group and an OH group.
17α-Estradiol (Impurity)
Impurities Data Field
Oxidation at C6
6-Ketoethinyl Estradiol (Impurity)
Impurities Data Field
One of the Hs of C6 in EE is replaced with an OH group
6β-Hydroxyethinyl Estradiol (Impurity)
Impurities Data Field
Oxidation at C6 of EE
6β-Hydroxyethinyl Estradiol (Impurity)
Impurities Data Field
The C17 hydroxyl group of EE becomes a C17 carbonyl group in this impurity
Estrone (Impurity)
Impurities Data Field
Oxidation of EE at C17; synthetic impurity
Estrone (Impurity)
Impurities Data Field
8-dehydroethinyl estradiol is an intermediate in the ethinylation of estrone and the δ8 double bond easily isomerizes to the δ9(11) position.
9(11)-Dehydroethinyl Estradiol (Impurity)