1. APIs
  2. Nestorone
  3. Impurities
  4. 3-Deoxo-3-ethynyl-3,5-diene Nestorone Derivative

3-Deoxo-3-ethynyl-3,5-diene Nestorone Derivative

Structure

Notes

UV shift

MOLECULAR FORMULA

C25H30O3

References

STRUCTURAL DIFFERENCE

Conversion of C3 ketone to ethinyl group. Reduction of C4-C5 double bond. Double bonds between C3-C4, C5-C6.

References

SPECTRA

UV shift

library_books

References

  1. Görög, S.; Babják, M.; Balogh, G.; Brlik, J.; Dravecz, F.; Gazdag, M.; Horváth, P.; Laukó, A.; Varga, K. Estimation of impurity profiles of drugs and related materials Part 19: Theme with variations. Identification of impurities in 3-oxosteroids. Journal of Pharmaceutical and Biomedical Analysis.1998, 18 (4), 511–525. 1998; 18:511-25.
    2. (View all citations for this reference)

SOURCE

Ethinylation

References

References

  1. Görög, S.; Babják, M.; Balogh, G.; Brlik, J.; Dravecz, F.; Gazdag, M.; Horváth, P.; Laukó, A.; Varga, K. Estimation of impurity profiles of drugs and related materials Part 19: Theme with variations. Identification of impurities in 3-oxosteroids. Journal of Pharmaceutical and Biomedical Analysis.1998, 18 (4), 511–525. 1998; 18:511-25.
    2. (View all citations for this reference)