17-Epi-Norethisterone

Structure

Other Names & Identifiers

  • BP Norethisterone Impurity G
  • 17-hydroxy-19-norpregn-4-en-20-yn-3-one
  • Impurity 3 (Gorog 1987)

Notes

Stereoisomer

Source

Byproduct of ethynylation step

library_books

References

  1. Gorog SH, B. Analysis of Steroids. 38. The use of high-performance liquid chromatography with diode-array UV detection for estimating impurity profiles of steroid drugs. Journal of Chromatography. 1987; 400:177-86.
  2. (View all citations for this reference)

Spectra

HPLC, UV

library_books

References

  1. Gorog SH, B. Analysis of Steroids. 38. The use of high-performance liquid chromatography with diode-array UV detection for estimating impurity profiles of steroid drugs. Journal of Chromatography. 1987; 400:177-86.
  2. (View all citations for this reference)

Spectra

LC, UV 254 nm

library_books

References

  1. British Pharmacopoeia 2014: Norethisterone API
  2. (View all citations for this reference)
  3. European Pharmacopoeia 8.2 Norethisterone
  4. (View all citations for this reference)

Limits

0.2%

References

  1. British Pharmacopoeia 2014: Norethisterone API
  2. (View all citations for this reference)
  3. European Pharmacopoeia 8.2 Norethisterone
  4. (View all citations for this reference)
  5. British Pharmacopoeia 2017: Norethisterone monograph.
  6. (View all citations for this reference)
  7. Gorog SH, B. Analysis of Steroids. 38. The use of high-performance liquid chromatography with diode-array UV detection for estimating impurity profiles of steroid drugs. Journal of Chromatography. 1987; 400:177-86.
  8. (View all citations for this reference)