Citations for: British Pharmacopoeia 2014: Norethisterone API

Entry Type
Name
Value
Parent Entry
Physical & Chemical Properties Data Field
Appearance
White or yellowish white, odorless, crystalline powder
Norethindrone (API)
Physical & Chemical Properties Data Field
Solubility
Insoluble in water, soluble in chloroform and dioxane, sparingly soluble in acetone and anhydrous ethanol. Slightly soluble in diethyl ether.
Norethindrone (API)
Impurity
17-Hydroxy-19-nor-17α-pregn-4,6-dien-20-yn-3-one
N/A
Impurities Data Field
Spectra
LC, UV 254 nm
17-Hydroxy-19-nor-17α-pregn-4,6-dien-20-yn-3-one (Impurity)
Impurity
Norandrostenedione
N/A
Impurities Data Field
Spectra
LC, UV 254 nm
Norandrostenedione (Impurity)
Impurity
17-Hydroxy-19-nor-17α-pregna-5-en-20-yn-3-one
N/A
Impurities Data Field
Spectra
LC, UV 210 nm
17-Hydroxy-19-nor-17α-pregna-5-en-20-yn-3-one (Impurity)
Impurities Data Field
Spectra
LC, UV 210 nm
17-Hydroxy-19-nor-17α-pregn-5(10)-en-20-yn-3-one (Impurity)
Impurities Data Field
Spectra
LC, UV 254 nm
3-Ethynyl-10-nor-17α-pregna-3,5-dien-20-yn-17-ol (Impurity)
Impurities Data Field
Spectra
LC, UV 254 nm
3-Ethoxy-10-nor-17α-pregna-3,5-dien-20-yn-17-ol (Impurity)
Impurity
17-Epi-Norethisterone
N/A
Impurity
6β-Hydroxynorethisterone
N/A
Impurities Data Field
Spectra
LC, UV 254 nm
6β-Hydroxynorethisterone (Impurity)
Impurity
Norethindrone
N/A
Impurity
3-Oxo-19-nor-17α-pregn-5(10)-en-20-yn-17-yl Acetate
N/A
Impurity
3-Oxo-19-nor-17α-pregn-5-en-20-yn-17-yl Acetate
N/A
Impurity
6β-Acetyl-3-oxo-19-nor-17α-pregn-4-en-20-yn-17-yl Acetate
N/A
Impurity
3,20-Dioxo-19-nor-17α-pregn-4-en-17-yl Acetate
N/A
Impurity
6β-Hydroxynorethindrone Acetate
N/A
Impurity
6-Ketonorethindrone Acetate
N/A
Impurity
3-(1-methylethoxy)-19-nor-17α-pregn-3,5-dien-20-yn-17-yl Acetate
N/A
Impurity
3-Ethoxy-19-nor-17α-pregn-3,5-dien-20-yn-17-yl Acetate
N/A
Impurities Data Field
Spectra
LC, UV 254 nm
17-Epi-Norethisterone (Impurity)
Physical & Chemical Properties Data Field
Specific Optical Rotation
-32.0 to -37.0 (dried)
-31.7 °C in chloroform
Norethindrone (API)