1. APIs
  2. Medroxy­progesterone Acetate
  3. Metabolites

MPA Metabolites

Name Structure Notes
1,2-Dehydromedroxyprogesterone Acetate structure Proposed structure of an MPA metabolite observed in MPA incubation with human liver microsomes.
2β,6β-Dihydroxymedroxyprogesterone Acetate structure Proposed structure of an MPA metabolite observed in MPA incubation with human liver microsomes.
Other MPA Metabolites Very little is known about the metabolism of MPA. Other metabolites may result from modifications at C17 and C21, and/or ring A reduction.
1β-hydroxymedroxyprogesterone acetate structure Result of hydroxylation by cytochrome P450 3A4.
2β-hydroxymedroxyprogesterone acetate structure Result of hydroxylation by cytochrome P450 3A4.
6β-hydroxymedroxyprogesterone acetate structure Result of hydroxylation by cytochrome P450 3A4.