Citations for: Hapgood, J. P.; Africander, D.; Louw, R.; Ray, R. M.; Rohwer, J. M., Potency of progestogens used in hormonal therapy: toward understanding differential actions. J Steroid Biochem Mol Biol 2013, 142, 39-47.

Entry Type
Name
Value
Parent Entry
Pharmacology Data Field
Androgen Receptor Activity
Reported as weakly effective to effective agonist.
Medroxy­progesterone Acetate (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Nestorone (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
No activity
Medroxy­progesterone Acetate (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Medroxy­progesterone Acetate (API)
Pharmacology Data Field
Androgen Receptor Activity
Binds but no agonist activity. "Weak," "partial" or "moderate" antagonist.
Nomegestrol Acetate (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
No activity
Nomegestrol Acetate (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Nomegestrol Acetate (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
Agonist
Chlormadinone Acetate (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Chlormadinone Acetate (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
Agonist
Cyproterone Acetate (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
No activity
Cyproterone Acetate (API)
Pharmacology Data Field
Androgen Receptor Activity
Antagonist
Progesterone (API)
Pharmacology Data Field
Glucocorticoid Receptor Activity
"weak partial agonist" (Africander, Hapgood), activates GR "minimally" (Turgeon), "active" (Ruan, Lello)
Progesterone (API)
Pharmacology Data Field
Mineralocorticoid Receptor Activity
"weak partial agonist" (Africander), active agonist (Bartsch). Antagonist.
Progesterone (API)