1. APIs
  2. Ethinyl Estradiol
  3. Ethinyl Estradiol Metabolites

Ethinyl Estradiol Metabolites

Name Structure Notes
16β-hydroxyethinyl estradiol structure Contributes to metabolism only to a small extent.
6α-hydroxyethinyl estradiol structure Contributes to metabolism only to a small extent.
4-hydroxyethinyl estradiol structure Contributes to metabolism only to a small extent. Can be converted to methoxy EE by catechol O-methyltransferase.
2-hydroxyethinyl estradiol structure Major metabolite. Formed by CYP3A4. Can be converted to the methoxy EE by catechol O-methyltransferase.