1. APIs
  2. Ethinyl Estradiol
  3. Ethinyl Estradiol Metabolites
  4. 4-hydroxyethinyl estradiol

4-hydroxyethinyl estradiol

Structure

MOL SDF CML

Source

Hydroxylation by CYP3A4

Notes

Contributes to metabolism only to a small extent. Can be converted to methoxy EE by catechol O-methyltransferase.

References

  1. Kuhl, H., Pharmacology of estrogens and progestogens: influence of different routes of administration. Climacteric 2005, 8 Suppl 1, 3-63.
    2. (View all citations for this reference)
  2. Stanczyk FZ. All progestins are not created equal. Steroids. 2003; 68:879-90.
    3. (View all citations for this reference)