Citations for: Stanczyk FZ. All progestins are not created equal. Steroids. 2003; 68:879-90.

Entry Type
Name
Value
Parent Entry
Metabolites
N/A
Metabolites
N/A
Metabolites
N/A
Pharmacology Data Field
  • Oral: Around 45%
  • Vaginal Ring: 55%
Ethinyl Estradiol (API)
Metabolites
N/A
Metabolites
N/A
Metabolites Data Field
"The 5α-reduction of NET, even if confers a relatively high binding affinity to the AR, diminishes its androgenic potency."
3α,5α-Tetrahydronorethindrone (Metabolite)
Metabolites Data Field
"The 5α-reduction of NET, even if confers a relatively high binding affinity to the AR, diminishes its androgenic potency."
3β,5α-Tetrahydronorethindrone (Metabolite)
Metabolites Data Field
selectively activates ERα. "Able to activate gene transcription via ER, although its binding affinity is lower than estradiol."
3β,5α-Tetrahydronorethindrone (Metabolite)
Metabolites
N/A
Metabolites
N/A