3α,5β-tetrahydrolevonorgestrel

Structure

Source

Reduction of C3 ketone to a hydroxyl and reduction of C4-C5 double bond.

Notes

Major metabolite. Also found as sulfate and glucuronide conjugates.

References

  1. Besse, J. P.; Garric, J., Progestagens for human use, exposure and hazard assessment for the aquatic environment. Environ. Pollut. 2009, 157 (12), 3485-3494.
  2. (View all citations for this reference)
  3. Stanczyk FZ. All progestins are not created equal. Steroids. 2003; 68:879-90.
  4. (View all citations for this reference)
  5. Hazardous Substances Data Bank (View all citations for this reference)
  6. Stanczyk FZR, S. Metabolism of levonorgestrel, norethindrone, and structurally related contraceptive steroids. 1990; 42:67-96.
  7. (View all citations for this reference)