4-Hydroxyestradiol

Structure

CASRN

5976-61-4

Notes

Formed by CYP1B1 in the liver. Minor pathway in liver but is formed in larger amount in extrahepatic tissues. Thought to be the most carcinogenic of all estradiol metabolites. Can bind to estrogen receptors.

Molecular Formula

C18H24O3

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References

Molecular Weight

288.39 g/mol

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References