Citations for: British Pharmacopoeia 2014: Medroxyprogesterone Acetate API

Entry Type
Name
Value
Parent Entry
Impurity
17β-Hydroxy-6,17α-dimethyl-D-homoandrost-4-en-3,17-dione
N/A
Impurity
Hydroxyprogesterone acetate
N/A
Impurity
Megestrol Acetate
N/A
Impurity
4,5-Dihydromedroxyprogesterone Acetate
N/A
Impurity
6-Methylenehydroxyprogesterone Acetate
N/A
Impurity
6-Epimedroxyprogesterone Acetate
N/A
Physical & Chemical Properties Data Field
Appearance
White or almost white crystalline powder, odorless.
Medroxy­progesterone Acetate (API)
Physical & Chemical Properties Data Field
Solubility
Practically insoluble in water. Slightly soluble in diethyl ether. Freely soluble in chloroform and dichloromethane. Soluble in acetone and dioxane. Sparingly soluble in ethanol and methanol.
Medroxy­progesterone Acetate (API)
Physical & Chemical Properties Data Field
Specific Optical Rotation
+47 to +53 (dried substance 0.250 g in acetone diluted to 25 mL).
+45 to +51 deg, 10 mg per mL in dioxane.
+61° in chloroform
Medroxy­progesterone Acetate (API)
Impurity
6α,17α-Dimethyl-3,17-dioxo-D-homoandrost-4-en-17α-yl Acetate
N/A
Impurity
Medroxyprogesterone
N/A