Entry Type
Name
Value
Parent Entry
Impurities Data Field
5-membered ring expands to a 6-membered ring
17β-Hydroxy-6,17α-dimethyl-D-homoandrost-4-en-3,17-dione (Impurity)
Impurities Data Field
The methyl group on C6 of MPA is replaced with an H group
Hydroxyprogesterone acetate (Impurity)
Impurities Data Field
The C6-C7 single bond of MPA is replaced with a C6=C7 double bond, resulting in loss of chirality at C6.
Megestrol Acetate (Impurity)
Impurities Data Field
White or almost white, crystalline powder
Megestrol Acetate (Impurity)
Impurities Data Field
About 217° C; 218.0-220.0° C
Megestrol Acetate (Impurity)
Impurities Data Field
Soluble in acetone, sparingly soluble in ethanol (96 per cent). Dissolves in methylene chloride (2.50 g/25.0 mL)
Megestrol Acetate (Impurity)
Impurities Data Field
+14 to +17 (dried substance)
Megestrol Acetate (Impurity)
Impurities Data Field
Protected from light
Megestrol Acetate (Impurity)
Impurities Data Field
Inversion of stereocenter at C6 of MPA; epimer of MPA
6-Epimedroxyprogesterone Acetate (Impurity)
Impurities Data Field
The ester group is hydrolyzed to an OH group
Medroxyprogesterone (Impurity)